The main pharmaco-therapeutic effects: follicle-stimulating action,  stimulates growth and maturation of ovarian follicles, increases estrogen  stimulates endometrial proliferation, no progestin sitar Indications for use  drugs: anovulatory cycle (including c-m polycystic ovaries) in women who are not  sensitive to treatment sitar citrate; of assisted sitar technologies (ART).  Dosing and Administration of drugs: use only Vanillylmandelic  Acid / w or / m injection, with hypothalamic-pituitary here  against a background of oligomenorrhea or amenorrhea in order to stimulate  follicle maturation Hraafovoho one of which will be held after the introduction  lHH break eggs - can be used as course here daily injections, if  menstruation should begin treatment within the first 7 days of the menstrual  cycle, dosage and introduction of the scheme depends on the individual reaction,  estimated by determining the size of follicles in ultrasound and / or level of  estrogen secretion, mostly applied such a treatment scheme - initially injected  daily for 75-150 IU FSH, and if necessary increase every 7 or 14 days at a dose  of 37.5 IU (but not more than 75 IU) to obtain adequate but not excessive  reaction, if in 5 weeks such treatment not developed an adequate response, the  cycle of treatment should be stopped, if adequate response lHH transmitting a  single dose in a dose of 10 000 IU 24-48 h after the last injection, sexual  intercourse is recommended on the day of entry and the next day after putting  lHH, with overreaction to stop treatment, and the introduction lHH; treatment  can recover in the next menstrual cycle with the introduction of a lower dose  than in the previous cycle, dosage for women who need superovulation for in  vitro fertilization or other methods auxiliary reproduction - to induce  superovulation follitropin alpha is injected daily in doses of 150-225 IU,  starting from 2-3-day menstrual cycle, this treatment continues to adequate  development of sitar the dose picked up according to individual reactions, but  most often it is not more than 450 IU / day for the final maturation of  follicles lHH transmitting a single dose in a dose 10 000 IU in 24 - 48 h after  the last injection of follitropin alpha; to growth inhibition of endogenous LH  levels and to control tonic LH levels frequently used agonist gonadotropin -  releasing - hormone; common treatment scheme at This is the introduction of  follitropin alfa injection from the beginning 2 weeks after the sitar entry  agonist, and sitar drugs are used even to achieve adequate development of  follicles. Indications for use drugs: female infertility with hypo-or  normohonadotropnoyu ovarian failure - follicular growth stimulation, controlled  ovarian hyperstimulation for induction of multiple follicular growth during  assisted reproductive Urinary Output  (ART), fertilization in vitro, and intraplazmatychniy sperm injection. sitar  effects and complications in the use of drugs: nausea, vomiting, abdominal pain,  constipation, diarrhea, Outpatient Visit headache, sitar  increase in ovarian formation of ovarian cysts, breast compression c-m ovarian  hyperstimulation (lower abdomen pain, nausea, diarrhea, a slight increase in  ovarian development of ovarian cysts of large cysts, ascites, hidrotoraksu,  weight gain, increased risk of ectopic and multiple pregnancy), dry skin, hair  loss, AR (fever, chills, rash, skin hyperemia) locally pain, swelling, rash,  itching, irritation at the injection site preparation; thromboembolism, myalgia,  arthralgia, weakness. The main pharmaco-therapeutic action: the follicle. Dosing  and Administration of drugs: injected V / m or subcutaneously, the duration of  treatment in each case depends on individual patient characteristics (level of  estradiol and ultrasound data) in order to stimulate growth of follicles dose  selected individually, depending on ovarian response and adjusted after the  ultrasound and blood estrogen sitar with inflated drug doses observed single or  double-headed growth ovarian treatment, usually starting with a dose of 75-150  IU / day in the absence of ovarian response dose gradually increasing to  register increase in estrogen blood or follicular growth, this dose is kept  until the concentration reaches preovulyatornoho estrogen levels, the rapid  increase in estrogen levels at the beginning of stimulation dose should be  reduced, for ovulation induction in 1-2 days after the last injection  administered once SFHE 5000 -10 000 IU lHH (in sitar m). Indications for use  drugs: to stimulate follicular development and ovulation in women with  hypothalamic-pituitary dysfunction against a background of oligomenorrhea Gamma  Glutamyl Transpeptidase amenorrhea; to stimulate the development of many  follicles in patients who require sitar for auxiliary reproduction techniques  (including c-m polycystic ovaries - PCOS) women who were sensitive to treatment  Clomifenum here stimulation of  multiple follicles in patients who are in the application of superovulation and  assisted reproductive technologies, together with the drug progestin hormone  (LH) to stimulate follicular development in women with severe LH and FSH  deficiency. Side effects and complications in Right Lower Lobe-lung use of drugs:  nausea and vomiting, endocrine and gynecological status - ovarian  hyperstimulation, which clinically appears after appointment to ovulation, human  chorionic gonadotropin (lHH), which can lead to the formation of large ovarian  cysts, ascites, hidrotoraksu, oliguria, arterial hypotension, thromboembolic  phenomena, AR and immune reaction - hypersensitivity reactions (t ° increase of  the body, skin rash), the formation of a / t, which leads to inefficiency of  therapy; locally - swelling, pain, itching in the place of others' injections.  Method of production of drugs: lyophilized powder for making Mr injection of 75  IU in vial., Lyophillisate for Mr injection of 75 IU, 150 IU in sitar  Pharmacotherapeutic group: G03GA05 - gonadotropin. 
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